Description
Chicken Zucchini Casserole is a comforting, family-friendly main dish featuring tender chicken, fresh zucchini, a savory stuffing topping, and a creamy sauce. This casserole blends diced chicken breast, fresh zucchini, onion, mozzarella, cream of chicken soup, and sour cream under a golden, buttery stuffing crust. Perfect for busy weeknights or potlucks, it’s creamy, delicious, and easy to prepare ahead, making it a go-to recipe for sharing or meal prep.
Ingredients
- 6 oz boxed stuffing mix
- 1/2 cup butter, melted
- 4 diced zucchini (about 4–5 cups bite-size pieces)
- 3 boneless chicken breasts, cooked and diced
- 1/2 cup shredded mozzarella cheese (optional)
- 10 1/2 oz canned cream of chicken soup
- 1/2 onion, diced
- 1/2 cup sour cream
Instructions
- Preheat oven to 350°F.
- Combine stuffing mix and melted butter in a large bowl.
- Set aside 1/2 cup of the mixture for topping.
- Add zucchini, cooked chicken, mozzarella cheese, cream of chicken soup, diced onion, and sour cream to the remaining stuffing mixture.
- Spread the mixture evenly in a 9×13 inch glass pan sprayed with cooking spray.
- Sprinkle the reserved stuffing mix on top.
- Bake uncovered for 40-50 minutes until cooked through and golden brown.
Notes
For a lighter version, substitute Greek yogurt for sour cream or use low-sodium soup. Rotisserie chicken works for quick prep. If zucchini releases excess water, squeeze lightly with a towel before mixing. Make ahead by assembling up to a day in advance and refrigerating; bake just before serving. Store leftovers in an airtight container in the fridge for up to 4 days, or freeze for up to 2 months. If the topping browns too fast, cover loosely with foil.
- Prep Time: 15 minutes
- Cook Time: 45 minutes
- Category: Main Course
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1/8 casserole
- Calories: 320
- Sugar: 4g
- Sodium: 720mg
- Fat: 17g
- Saturated Fat: 9g
- Unsaturated Fat: 7g
- Trans Fat: 0g
- Carbohydrates: 22g
- Fiber: 2g
- Protein: 19g
- Cholesterol: 65mg